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While both medications showed a significant weight loss benefit, after 72 weeks on treatment, people treated with Zepbound lost 20% of their body weight, compared to people on Wegovy who lost just under 14%

Consult your doctor if you are pregnant, nursing, taking medication or facing health problems

Second , Hb associates at its residues 3443 with the oxygenase domain of eNOS in a macromolecular complex (Straub et al., 2014a), an interaction dictated by amino acids 36 SFPT 39 in the Hb sequence (Keller et al., 2022)

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This is not a reason to avoid Retatrutide entirely in this population, but it is a reason to monitor blood sugar closely during dose escalation and to have a clear plan for hypoglycemia management